I opened the incubator door, and a familiar whiff of an earthy, repulsive odor attacked my nostrils. I held my breath and slowly took out a stack of yellow gel plates covered with small white dots. This could be the day, I hoped to myself. This was just another round of mutation screening, trying to find that one special bacterial colony with that one specific mutation that could prove our hypothesis.
The Department of Biology hosted a seminar on Thursday, Oct. 26 featuring Alison Xie, an assistant research professor of surgery-urology at the University of Colorado Anschutz Medical Campus. The talk, titled “Glial-Neuron Interactions in Sensory Ganglia Alleviate the Symptoms of Chronic Pain in Mice,” discussed Xie’s research on how Gq-GPCR activation in satellite glial cells (SGCs) of the sensory ganglia can produce analgesic effects in mouse models.
Nilanjan Chatterjee, a professor of biostatistics and genetic epidemiology at the School of Medicine and also recognized as a Bloomberg Distinguished Professor, collaborated on a machine-learning model that would improve the predictive ability of polygenic risk scores in non-European populations. This research, a collaboration with the Harvard T.H. Chan School of Public Health and Haoyu Zhang from the National Cancer Institute, was recently published in Nature Genetics.
It’s spooky season, and the following scientific findings sure are a treat! Scientific news this week ranges from as microscopic as gut microbiome to as macroscopic as Mars.
As we hop back into school after Fall Break, let’s review some of the biggest headlines in science. This week features stories about malaria vaccines, weight loss drugs, gravitational wave observations and lithium-ion batteries.
Rajiv McCoy, an assistant professor in the Department of Biology, and his collaborators at London Women’s Clinic in the U.K. discovered a strong correlation between chromosome abnormalities, embryo arrest and low blastocyst morphological grading of the in vitro fertilization (IVF) of human preimplantation embryos. Their results were recently published in Genome Medicine.
Orion Weller is a third-year doctoral student affiliated with the Center for Language and Speech Processing (CLSP) advised by Benjamin Van Durme and Dawn Lawrie. He is currently teaching a Hopkins Engineering Applications and Research Tutorials (HEART) course titled Reasoning with ChatGPT in which he discusses the contexts and relevance of his research.
On Thursday, Oct. 12, Associate Professor in the Department of Molecular Biosciences at Northwestern University Sadie Wignall shared her findings on the mechanisms oocytes employ to regulate spindles without centrosomes during meiosis.
Associate Professor in the Department of Mathematics at Creighton University Nathan Pennington delivered a guest lecture to Ex Numera, the undergraduate mathematics club, on Oct. 9. It was their third speaker of the semester. The talk, titled “Why You Should Take Differential Equations,” discussed the issues with typical first-semester differential equations courses in comparison to what the topic looks like.
On October 7, the Johns Hopkins Institute for Clinical and Translational Research (ICTR) celebrated the 13th anniversary of the Henrietta Lacks Memorial Lecture, a symposium of lectures related to the lasting legacy of Henrietta Lacks, the ethical implications of her treatment by Hopkins and the future of clinical research.
While taking the class Cognitive Neuroscience with Professor Mick Bonner in my freshman year, I heard my future PI Dr. Elisabeth Marsh present the five guiding principles she employs while working at the intersection of stroke research and clinical medicine. I joined the Marsh Lab soon after. While I was interested in learning more about stroke, I did not understand the true complexities of the disease until the fall of 2022, when my grandpa suffered from a stroke.
In the Institute for Computational Medicine (ICM) special seminar series on Oct 3., Assistant Professor at the Integrated Mathematical Oncology Department at H. Lee Moffitt Cancer Center & Research Institute Renee Brady shared insights on using minimally invasive biomarkers to predict treatment responses.
In a groundbreaking development, a team of Hopkins researchers has unveiled an innovation in HIV therapy that promises to transform the lives of individuals with the virus. This research, published in the Journal of the American Chemical Society, offers a novel method to maintain clinically sufficient drug levels through an injectable solution that autonomously forms into a hydrogel.
In the Sept. 26 Department of Computer Science (CS) Distinguished Lecture Series, Stefano Soatto, a CS professor from the University of California, Los Angeles, and Vice President of Applied Science for Amazon Web Services AI, spoke about the learning and controllability of large language models (LLMs) and computer vision.
For many of us, this past week was marked by late nights studying for midterms and catching up on work in Brody Learning Commons. Yet, for the global scientific community, it was marked by the announcements of the 2023 Nobel Prizes!
Jeong Hee Kim and Lintong Wu, two doctoral candidates in the Department of Mechanical Engineering at Johns Hopkins University, contributed to a study that examined an efficient screening method to detect therapy-induced senescent (TIS) cells that can increase the chance of therapy resistance and cancer relapse. This study, recently published in Science Advances, was in collaboration with researchers from the Polytechnic University of Milan and the National Research Council in Italy.
One-lung ventilation (OLV), a practice required for many chest procedures, involves the ventilation of one lung and the deflation of the other but has many risks. Amid the height of the pandemic, the OnPoint Ventilation team — initiated as part of the Biomedical Engineering (BME) Design Team program — embarked on a mission to invent a safer instrument for this critical procedure, resulting in the Bronchosleeve, which will be presented at this year's Collegiate Inventors Competition in Washington, D.C.
The Department of Electrical and Computer Engineering (ECE) hosted a seminar on Sept. 26 to showcase the research conducted by Assistant Professor of Biomedical Engineering at Duke University Roarke Horstmeyer. The talk, titled "Computational 3D Video Microscopy with Multi-camera Arrays," explained the design and algorithm behind the state-of-the-art multi-camera array microscopes (MCAMs) and several use cases.
As an undergraduate researcher, every experiment I undertake reaffirms my childhood belief: Understanding the intricacies of the microscopic can have a profound impact on the broader scope of human health.
The study found that Molnupiravir could be linked to the transmission of specific SARS-CoV-2 variants. This is thought to be possible if SARS-CoV-2 patients who underwent Molnupiravir treatment still had a residual viral load that was likely unable to cause severe symptoms but could cause future spread.
